PROGNOSTIC ROLE OF C-REACTIVE PROTEIN AND CARDIAC EVENT RISK

This review focuses on endothelium interaction with inflammatory mediators. C-reactive protein (CRP) plays a role in inflammation activation, endothelin-1 production increase, and lipid peroxidation enhancement, which results in endothelial dysfunction. The other consequences include vasoconstrictio...

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Bibliographic Details
Main Authors: O. V. Milyutina, E. N. Chicherina
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC  2011-02-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/1089
Description
Summary:This review focuses on endothelium interaction with inflammatory mediators. C-reactive protein (CRP) plays a role in inflammation activation, endothelin-1 production increase, and lipid peroxidation enhancement, which results in endothelial dysfunction. The other consequences include vasoconstriction, blood pressure increase, thrombosis, and, finally, cardiovascular events.
ISSN:1560-4071
2618-7620