Folding Free Energies of 5'-UTRs Impact Post-Transcriptional Regulation on a Genomic Scale in Yeast.

Using high-throughput technologies, abundances and other features of genes and proteins have been measured on a genome-wide scale in Saccharomyces cerevisiae. In contrast, secondary structure in 5'-untranslated regions (UTRs) of mRNA has only been investigated for a limited number of genes. Her...

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Bibliographic Details
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-12-01
Series:PLoS Computational Biology
Online Access:http://dx.doi.org/10.1371/journal.pcbi.0010072