Targeting Histone Demethylase LSD1/KDM1a in Neurodegenerative Diseases

The autophagy-lysosome pathway sustains cellular homeostasis and is a protective mechanism against neurodegenerative diseases. Recent findings highlight the role of the histone demethylases LSD1/LDM1A as a pivotal regulator of autophagy process, by controlling the mTORC1 cascade, in neuroblastoma ce...

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Bibliographic Details
Main Authors: Susanna Ambrosio, Barbara Majello
Format: Article
Language:English
Published: SAGE Publishing 2018-03-01
Series:Journal of Experimental Neuroscience
Online Access:https://doi.org/10.1177/1179069518765743

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