Reversed metabolic reprogramming as a measure of cancer treatment efficacy in rat C6 glioma model.
<h4>Background</h4>Metabolism in tumor shifts from oxidative phosphorylation to inefficient glycolysis resulting in overproduction of lactate (Warburg effect), and cancers may be effectively treated if this imbalance were corrected. The aim of this longitudinal study of glioblastoma in a...
Main Authors: | Keshav Datta, Mette H Lauritzen, Milton Merchant, Taichang Jang, Shie-Chau Liu, Ralph Hurd, Lawrence Recht, Daniel M Spielman |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0225313 |
Similar Items
-
Alterations in cerebrospinal fluid proteins in a presymptomatic primary glioma model.
by: John C Whitin, et al.
Published: (2012-01-01) -
Metabolic Reprogramming in Glioma
by: Elizabeth A. Stoll, et al.
Published: (2017-04-01) -
Metabolic reprogramming in mutant IDH1 glioma cells.
by: Jose L Izquierdo-Garcia, et al.
Published: (2015-01-01) -
Lactate Reprograms Energy and Lipid Metabolism in Glucose-Deprived Oxidative Glioma Stem Cells
by: Noriaki Minami, et al.
Published: (2021-05-01) -
A proteomic clock for malignant gliomas: The role of the environment in tumorigenesis at the presymptomatic stage.
by: Le Zheng, et al.
Published: (2019-01-01)