CHBP induces stronger immunosuppressive CD127+ M-MDSC via erythropoietin receptor

CHBP induces stronger immunosuppressive CD127+ M-MDSC via erythropoietin receptor

Abstract Erythropoietin (EPO) is not only an erythropoiesis hormone but also an immune-regulatory cytokine. The receptors of EPO (EPOR)2 and tissue-protective receptor (TPR), mediate EPO’s immune regulation. Our group firstly reported a non-erythropoietic peptide derivant of EPO, cyclic helix B pept...

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Bibliographic Details
Main Authors: Jiawei Li, Guowei Tu, Weitao Zhang, Yi Zhang, Xuepeng Zhang, Yue Qiu, Jiyan Wang, Tianle Sun, Tongyu Zhu, Cheng Yang, Ruiming Rong
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03448-7

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