One-step purification and characterization of alginate lyase from a clinical Pseudomonas aeruginosa with destructive activity on bacterial biofilm

Objective(s): Pseudomonas aeruginosais a Gram-negative and aerobic rod bacterium that displays mucoid and non-mucoid phenotype. Mucoid strains secrete alginate, which is the main agent of biofilms in chronic P. aeruginosa infections, show high resistance to antibiotics; consequently, the biological...

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Bibliographic Details
Main Authors: Parinaz Ghadam, Fatemeh Akhlaghi, Ahya Abdi Ali
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2017-05-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/article_8668_d9988b5c713c1b50fb14a72f80d86454.pdf