Cysteine redox potential determines pro-inflammatory IL-1beta levels.

Cysteine redox potential determines pro-inflammatory IL-1beta levels.

Cysteine (Cys) and its disulfide, cystine (CySS) represent the major extracellular thiol/disulfide redox control system. The redox potential (E(h)) of Cys/CySS is centered at approximately -80 mV in the plasma of healthy adults, and oxidation of E(h) Cys/CySS is implicated in inflammation associated...

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Bibliographic Details
Main Authors: Smita S Iyer, Carolyn J Accardi, Thomas R Ziegler, Roberto A Blanco, Jeffrey D Ritzenthaler, Mauricio Rojas, Jesse Roman, Dean P Jones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2657829?pdf=render

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