Effect of different blood purification methods on adipokines and flammatory factor in patients with diabetic nephropathy
Objective: To investigate the effect of in different type hemopurification techniques on adipokine and flammatory factor in diabetic nephropathy with maintenance hemodialysis (MHD). Methods: A total of 81 diabetic nephropathy patients were randomly divided into on hemodialysis group (HD, n=27), h...
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| Format: | Article |
| Language: | English |
| Published: |
Editorial Board of Journal of Hainan Medical University
2016-02-01
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| Series: | Journal of Hainan Medical University |
| Subjects: | |
| Online Access: | http://www.jhmuweb.net/PDF/201604/8.pdf |
| Summary: | Objective: To investigate the effect of in different type hemopurification techniques on
adipokine and flammatory factor in diabetic nephropathy with maintenance hemodialysis
(MHD). Methods: A total of 81 diabetic nephropathy patients were randomly divided into on
hemodialysis group (HD, n=27), hemodialysis with hemoperfusion group (HD+HP, n=27),
online hemodiafiltration group (OL-HDF, n=27). Levels of adiponectin, resistin, interleukin-6
(IL-6), and tumor necrosis factor (TNF-α) were tested and compared before and after
treatment. Results: Indicators of HD group have no statistical significance before and after
treatment. HD+HP and OL-HDF group adiponectin level increased significantly, resistin, IL-6
and TNF-α level decreased significantly before and after treatment; OL-HDF group resistin,
IL-6 and TNF-α level decreased more significantly than HD+HP group after treatment.
Conclusion: HD+HP and OL-HDF treatments have reliable curative effect on diabetic
nephropathy patients, which can regulate adiponectin, resistin, IL-6 and TNF-α level. Effect
of OL-HDF treatment eliminates resistin, IL-6 and TNF-α more markedly than HD+HP
treatment. |
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| ISSN: | 1007-1237 1007-1237 |