Oral Administration of Brain Protein Combined With Probiotics Induces Immune Tolerance Through the Tryptophan Pathway

Oral Administration of Brain Protein Combined With Probiotics Induces Immune Tolerance Through the Tryptophan Pathway

Excessive inflammation leads to secondary immune damage after traumatic brain injury (TBI). The intestinal mucosa is a key component of immune tolerance due to gut-brain axis regulation, but the curative effect is not optimal. Intestinal dysfunction impairs the establishment of immune tolerance in p...

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Bibliographic Details
Main Authors: Yongxin Hou, Lixia Xu, Sirong Song, Weijia Fan, Qiaoli Wu, Xiaoguang Tong, Hua Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
TBI
immune tolerance
probiotics
tryptophan
IDO
5-HT
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.634631/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2021.634631/full

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