Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis
When grown in the lab, Mycobacterium tuberculosis can form pellicle biofilms. Here, Trivedi et al. show that thiol reductive stress (induced by dithiothreitol) triggers rapid formation of thicker biofilms containing cellulose as well as antibiotic-tolerant, metabolically active bacteria.
Main Authors: | Abhishek Trivedi, Parminder Singh Mavi, Deepak Bhatt, Ashwani Kumar |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms11392 |
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