Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA.

Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA.

Next-generation sequencing of cell-free circulating solid tumor DNA addresses two challenges in contemporary cancer care. First this method of massively parallel and deep sequencing enables assessment of a comprehensive panel of genomic targets from a single sample, and second, it obviates the need...

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Bibliographic Details
Main Authors: Richard B Lanman, Stefanie A Mortimer, Oliver A Zill, Dragan Sebisanovic, Rene Lopez, Sibel Blau, Eric A Collisson, Stephen G Divers, Dave S B Hoon, E Scott Kopetz, Jeeyun Lee, Petros G Nikolinakos, Arthur M Baca, Bahram G Kermani, Helmy Eltoukhy, AmirAli Talasaz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0140712

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