Bupleuri radix extract ameliorates impaired lipid metabolism in high-fat diet-induced obese mice via gut microbia-mediated regulation of FGF21 signaling pathway

Bupleuri radix extract ameliorates impaired lipid metabolism in high-fat diet-induced obese mice via gut microbia-mediated regulation of FGF21 signaling pathway

Background: Obesity and its comorbidities are associated with abnormal lipid metabolism and gut microbiota dysbiosis. Bupleuri Radix is a medicinal plant used in traditional Chinese medicine with the prevention and treatment of obesity-related diseases. In this study, we aim to validate the regulati...

Full description

Bibliographic Details
Main Authors: Liucen Wu, Qian Yan, Fenglian Chen, Cheng Cao, Shuling Wang
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Metabolic disorder
Fibroblast growth factor-21
Gut microbiota
Obesity
Microbiome transplantation
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220313809

Similar Items

Similar Items