The treatment of autonomic dysfunction in tetanus

The treatment of autonomic dysfunction in tetanus

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We report a case of generalised tetanus in a 50-year-old female patient after sustaining a wound to her right lower leg. She developed autonomic dysfunction, which included labile hypertension alternating with hypotension and sweating. The autonomic dysfunction was treated successfully with a combin...

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Main Authors: T van den Heever, M G L Spruyt
Format: Article
Language:English
Published: Health and Medical Publishing Group 2017-07-01
Series:Southern African Journal of Critical Care
Online Access:http://www.sajcc.org.za/index.php/SAJCC/article/view/274/276
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spelling doaj-132fc4a4a5144e9a9ee2c2fd923a44702020-11-24T20:53:55ZengHealth and Medical Publishing GroupSouthern African Journal of Critical Care1562-82642078-676X2017-07-01331283110.7196/SAJCC.2017.v33i1.274The treatment of autonomic dysfunction in tetanusT van den Heever0M G L Spruyt1Department of Critical Care, Faculty of Health Sciences, University of the Free State, Bloemfontein, South AfricaDepartment of Critical Care, Faculty of Health Sciences, University of the Free State, Bloemfontein, South AfricaWe report a case of generalised tetanus in a 50-year-old female patient after sustaining a wound to her right lower leg. She developed autonomic dysfunction, which included labile hypertension alternating with hypotension and sweating. The autonomic dysfunction was treated successfully with a combination of morphine sulphate infusion, magnesium sulphate, and clonidine. She also received adrenaline and phenylephrine infusions as needed for hypotension. We then discuss the pathophysiology, clinical features and treatment options of autonomic dysfunction.http://www.sajcc.org.za/index.php/SAJCC/article/view/274/276
collection DOAJ
language English
format Article
sources DOAJ
author T van den Heever
M G L Spruyt
spellingShingle T van den Heever
M G L Spruyt
The treatment of autonomic dysfunction in tetanus
Southern African Journal of Critical Care
author_facet T van den Heever
M G L Spruyt
author_sort T van den Heever
title The treatment of autonomic dysfunction in tetanus
title_short The treatment of autonomic dysfunction in tetanus
title_full The treatment of autonomic dysfunction in tetanus
title_fullStr The treatment of autonomic dysfunction in tetanus
title_full_unstemmed The treatment of autonomic dysfunction in tetanus
title_sort treatment of autonomic dysfunction in tetanus
publisher Health and Medical Publishing Group
series Southern African Journal of Critical Care
issn 1562-8264
2078-676X
publishDate 2017-07-01
description We report a case of generalised tetanus in a 50-year-old female patient after sustaining a wound to her right lower leg. She developed autonomic dysfunction, which included labile hypertension alternating with hypotension and sweating. The autonomic dysfunction was treated successfully with a combination of morphine sulphate infusion, magnesium sulphate, and clonidine. She also received adrenaline and phenylephrine infusions as needed for hypotension. We then discuss the pathophysiology, clinical features and treatment options of autonomic dysfunction.
url http://www.sajcc.org.za/index.php/SAJCC/article/view/274/276
work_keys_str_mv AT tvandenheever thetreatmentofautonomicdysfunctionintetanus
AT mglspruyt thetreatmentofautonomicdysfunctionintetanus
AT tvandenheever treatmentofautonomicdysfunctionintetanus
AT mglspruyt treatmentofautonomicdysfunctionintetanus
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