The treatment of autonomic dysfunction in tetanus

We report a case of generalised tetanus in a 50-year-old female patient after sustaining a wound to her right lower leg. She developed autonomic dysfunction, which included labile hypertension alternating with hypotension and sweating. The autonomic dysfunction was treated successfully with a combin...

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Bibliographic Details
Main Authors: T van den Heever, M G L Spruyt
Format: Article
Language:English
Published: Health and Medical Publishing Group 2017-07-01
Series:Southern African Journal of Critical Care
Online Access:http://www.sajcc.org.za/index.php/SAJCC/article/view/274/276
Description
Summary:We report a case of generalised tetanus in a 50-year-old female patient after sustaining a wound to her right lower leg. She developed autonomic dysfunction, which included labile hypertension alternating with hypotension and sweating. The autonomic dysfunction was treated successfully with a combination of morphine sulphate infusion, magnesium sulphate, and clonidine. She also received adrenaline and phenylephrine infusions as needed for hypotension. We then discuss the pathophysiology, clinical features and treatment options of autonomic dysfunction.
ISSN:1562-8264
2078-676X