Topiramate and Metformin Are Effective Add-On Treatments in Controlling Antipsychotic-Induced Weight Gain: A Systematic Review and Network Meta-Analysis

Topiramate and Metformin Are Effective Add-On Treatments in Controlling Antipsychotic-Induced Weight Gain: A Systematic Review and Network Meta-Analysis

Background: Antipsychotic drugs may lead to side effects such as obesity, diabetes, dyslipidemia, and cardiovascular disease. The current systematic review and network meta-analysis analyzes and provides an update on the clinical performance of these add-ons in comparison to placebo on body weight a...

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Bibliographic Details
Main Authors: Chuanjun Zhuo, Yong Xu, Sha Liu, Jing Li, Qishi Zheng, Xiangyang Gao, Shen Li, Rixing Jing, Xueqin Song, Weihua Yue, Chunhua Zhou, Rachel Upthegrove
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Pharmacology
Subjects:
antipsychotic-induced weight gain
network meta-analysis
pharmacological add-ons
topiramate
metformin
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01393/full

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