Methylphenidate Treatment of Cognitive Dysfunction in Adults After Mild to Moderate Traumatic Brain Injury: Rationale, Efficacy, and Neural Mechanisms

Methylphenidate Treatment of Cognitive Dysfunction in Adults After Mild to Moderate Traumatic Brain Injury: Rationale, Efficacy, and Neural Mechanisms

Positive effects of methylphenidate (MPH) on attention and cognitive processing speed have been reported in studies of patients with moderate to severe traumatic brain injury (TBI). Studies which have acquired functional brain imaging before and while using MPH have also found alteration of brain ac...

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Bibliographic Details
Main Authors: Harvey Levin, Maya Troyanskaya, JoAnn Petrie, Elisabeth A. Wilde, Jill V. Hunter, Tracy J. Abildskov, Randall S. Scheibel
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Neurology
Subjects:
traumatic brain injury
methylphenidate
clinical trials
imaging
dopamine
cognition
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00925/full

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