CDKN2A copy number and p16 expression in malignant pleural mesothelioma in relation to asbestos exposure

CDKN2A copy number and p16 expression in malignant pleural mesothelioma in relation to asbestos exposure

Abstract Background Deletion of the CDKN2A locus is centrally involved in the development of several malignancies. In malignant pleural mesothelioma (MPM), it is one of the most frequently reported genomic alteration. MPM is strongly associated with a patients’ asbestos exposure. However, the status...

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Bibliographic Details
Main Authors: Eeva Kettunen, Sauli Savukoski, Kaisa Salmenkivi, Tom Böhling, Esa Vanhala, Eeva Kuosma, Sisko Anttila, Henrik Wolff
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Cancer
Subjects:
Malignant pleural mesothelioma
CDKN2A
p16
Tumor stroma
Asbestos exposure
Online Access:http://link.springer.com/article/10.1186/s12885-019-5652-y

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http://link.springer.com/article/10.1186/s12885-019-5652-y

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