Immune response dynamics and Lutzomyia longipalpis exposure characterize a biosignature of visceral leishmaniasis susceptibility in a canine cohort.

Immune response dynamics and Lutzomyia longipalpis exposure characterize a biosignature of visceral leishmaniasis susceptibility in a canine cohort.

<h4>Background</h4>Reports have shown correlations between the immune response to vector saliva and Leishmaniasis outcome. We followed dogs in an endemic area for two years characterizing resistance or susceptibility to canine visceral leishmaniasis (CVL) according to Leishmania infantum...

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Main Authors: Manuela da Silva Solcà, Maiara Reis Arruda, Bruna Martins Macedo Leite, Tiago Feitosa Mota, Miriam Flores Rebouças, Matheus Silva de Jesus, Leila Denise Alves Ferreira Amorim, Valéria Matos Borges, Jesus Valenzuela, Shaden Kamhawi, Patrícia Sampaio Tavares Veras, Deborah Bittencourt Mothé Fraga, Claudia Ida Brodskyn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009137

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