Generation of functional salivary gland tissue from human submandibular gland stem/progenitor cells

Generation of functional salivary gland tissue from human submandibular gland stem/progenitor cells

Abstract Background Organ replacement regenerative therapy based on human adult stem cells may be effective for salivary gland hypofunction. However, the generated tissues are immature because the signaling factors that induce the differentiation of human salivary gland stem cells into salivary glan...

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Bibliographic Details
Main Authors: Yi Sui, Siqi Zhang, Yongliang Li, Xin Zhang, Waner Hu, Yanrui Feng, Jingwei Xiong, Yuanyuan Zhang, Shicheng Wei
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Stem Cell Research & Therapy
Subjects:
Human salivary gland stem cells
Organoids
Salivary gland regeneration
Xerostomia
FGF10
Mouse embryonic salivary gland mesenchyme
Online Access:http://link.springer.com/article/10.1186/s13287-020-01628-4

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http://link.springer.com/article/10.1186/s13287-020-01628-4

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