Apoptosis Deregulation and the Development of Cancer Multi-Drug Resistance

The ability of tumor cells to evade apoptosis is established as one of the hallmarks of cancer. The deregulation of apoptotic pathways conveys a survival advantage enabling cancer cells to develop multi-drug resistance (MDR), a complex tumor phenotype referring to concurrent resistance toward agents...

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Bibliographic Details
Main Authors: Christiana M. Neophytou, Ioannis P. Trougakos, Nuray Erin, Panagiotis Papageorgis
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/17/4363