Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review

Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review

A 48-year-old male with history of schizoaffective disorder on clozapine presented with chest pain, dyspnea, and new left bundle branch block. He underwent coronary angiography, which revealed no atherosclerosis. The patient’s workup was unrevealing for a cause for the cardiomyopathy and thus it was...

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Main Authors: Shahbaz A. Malik, Sarah Malik, Taylor F. Dowsley, Balwinder Singh
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2015/835952
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spelling doaj-1306ee841e3648fd831b7eecfd0fa93f2020-11-25T00:24:56ZengHindawi LimitedCase Reports in Cardiology2090-64042090-64122015-01-01201510.1155/2015/835952835952Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature ReviewShahbaz A. Malik0Sarah Malik1Taylor F. Dowsley2Balwinder Singh3Department of Internal Medicine, University of North Dakota School of Medicine and Health Sciences, Fargo, ND 58102, USADepartment of Internal Medicine, University of North Dakota School of Medicine and Health Sciences, Fargo, ND 58102, USADepartment of Cardiology, Sanford Health, Fargo, ND 58102, USADepartment of Psychiatry and Behavioral Science, University of North Dakota School of Medicine and Health Sciences, Fargo, ND 58102, USAA 48-year-old male with history of schizoaffective disorder on clozapine presented with chest pain, dyspnea, and new left bundle branch block. He underwent coronary angiography, which revealed no atherosclerosis. The patient’s workup was unrevealing for a cause for the cardiomyopathy and thus it was thought that clozapine was the offending agent. The patient was taken off clozapine and started on guideline directed heart failure therapy. During the course of hospitalization, he was also discovered to have a left ventricular (LV) thrombus for which he received anticoagulation. To our knowledge, this is the first case report of clozapine-induced cardiomyopathy complicated by a LV thrombus.http://dx.doi.org/10.1155/2015/835952
collection DOAJ
language English
format Article
sources DOAJ
author Shahbaz A. Malik
Sarah Malik
Taylor F. Dowsley
Balwinder Singh
spellingShingle Shahbaz A. Malik
Sarah Malik
Taylor F. Dowsley
Balwinder Singh
Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review
Case Reports in Cardiology
author_facet Shahbaz A. Malik
Sarah Malik
Taylor F. Dowsley
Balwinder Singh
author_sort Shahbaz A. Malik
title Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review
title_short Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review
title_full Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review
title_fullStr Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review
title_full_unstemmed Left Ventricular Thrombus as a Complication of Clozapine-Induced Cardiomyopathy: A Case Report and Brief Literature Review
title_sort left ventricular thrombus as a complication of clozapine-induced cardiomyopathy: a case report and brief literature review
publisher Hindawi Limited
series Case Reports in Cardiology
issn 2090-6404
2090-6412
publishDate 2015-01-01
description A 48-year-old male with history of schizoaffective disorder on clozapine presented with chest pain, dyspnea, and new left bundle branch block. He underwent coronary angiography, which revealed no atherosclerosis. The patient’s workup was unrevealing for a cause for the cardiomyopathy and thus it was thought that clozapine was the offending agent. The patient was taken off clozapine and started on guideline directed heart failure therapy. During the course of hospitalization, he was also discovered to have a left ventricular (LV) thrombus for which he received anticoagulation. To our knowledge, this is the first case report of clozapine-induced cardiomyopathy complicated by a LV thrombus.
url http://dx.doi.org/10.1155/2015/835952
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AT taylorfdowsley leftventricularthrombusasacomplicationofclozapineinducedcardiomyopathyacasereportandbriefliteraturereview
AT balwindersingh leftventricularthrombusasacomplicationofclozapineinducedcardiomyopathyacasereportandbriefliteraturereview
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