Production Strategies for Pentamer-Positive Subviral Dense Bodies as a Safe Human Cytomegalovirus Vaccine

Production Strategies for Pentamer-Positive Subviral Dense Bodies as a Safe Human Cytomegalovirus Vaccine

Infections with the human cytomegalovirus (HCMV) are associated with severe clinical manifestations in children following prenatal transmission and after viral reactivation in immunosuppressed individuals. The development of an HCMV vaccine has long been requested but there is still no licensed prod...

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Bibliographic Details
Main Authors: Patricia Gogesch, Inessa Penner, Steffi Krauter, Nicole Büscher, Leander Grode, Inci Aydin, Bodo Plachter
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Vaccines
Subjects:
cytomegalovirus
vaccine
dense bodies
congenital infection
safety vector
pentamer complex
gH/gL/UL128-131
Online Access:https://www.mdpi.com/2076-393X/7/3/104

Internet

https://www.mdpi.com/2076-393X/7/3/104

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