CORRECTION CHRONIC ISCHEMIA FINITE COMBINATION OF VARDENAFIL AND PENTOXIFYLLINE EXPERIMENT

CORRECTION CHRONIC ISCHEMIA FINITE COMBINATION OF VARDENAFIL AND PENTOXIFYLLINE EXPERIMENT

Experimental work conducted on Wistar rat line. Ischemia was simulated on the shin muscles of rats. Muscle ischaemia correction performed intragastric administration of pentoxifylline at a dose of 60 mg / kg of vardenafil dose of 0.9 mg / kg daily for 28 days and in combination vardenafil dose of 0....

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Main Authors: K. I. Lavrinenko, A. S. Belous, G. S. Mal, E. B. Artyushkova, E. A. Loyko
Format: Article
Language:Russian
Published: Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” 2016-10-01
Series:Кубанский научный медицинский вестник
Subjects:
эксперимент
хроническая ишемия
нижняя конечность
варденафил
пентоксифиллин
experiment
chronic ischemia of the lower limb
vardenafil
pentoxifylline
Online Access:https://ksma.elpub.ru/jour/article/view/595
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spelling doaj-12f48156bf63464e9e3d0c30d8bf48c32021-07-28T13:14:04ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442016-10-015848910.25207/1608-6228-2016-5-84-89595CORRECTION CHRONIC ISCHEMIA FINITE COMBINATION OF VARDENAFIL AND PENTOXIFYLLINE EXPERIMENTK. I. Lavrinenko0A. S. Belous1G. S. Mal2E. B. Artyushkova3E. A. Loyko4ГБОУ ВПО «Курский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииГБОУ ВПО «Курский государственный медицинский университет» Министерства здравоохранения Российской Федерации; ФГБОУ ВПО «Курский государственный университет» Минобрнауки Российской ФедерацииГБОУ ВПО «Курский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииГБОУ ВПО «Курский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииГБОУ ВПО «Курский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииExperimental work conducted on Wistar rat line. Ischemia was simulated on the shin muscles of rats. Muscle ischaemia correction performed intragastric administration of pentoxifylline at a dose of 60 mg / kg of vardenafil dose of 0.9 mg / kg daily for 28 days and in combination vardenafil dose of 0.09 mg / kg of pentoxifylline and 30 mg / kg for 7 days. Results were evaluated 21 and 28 hours. The level of microcirculatory perfusion expressed in units. Correction of muscle ischemia combination of vardenafil and pentoxifylline in small doses for 7 days stimulates angiogenesis and improves blood circulation in the distal extremities in proportion to the average therapeutic dose of vardenafil 28 days.https://ksma.elpub.ru/jour/article/view/595экспериментхроническая ишемиянижняя конечностьварденафилпентоксифиллинexperimentchronic ischemia of the lower limbvardenafilpentoxifylline
collection DOAJ
language Russian
format Article
sources DOAJ
author K. I. Lavrinenko
A. S. Belous
G. S. Mal
E. B. Artyushkova
E. A. Loyko
spellingShingle K. I. Lavrinenko
A. S. Belous
G. S. Mal
E. B. Artyushkova
E. A. Loyko
CORRECTION CHRONIC ISCHEMIA FINITE COMBINATION OF VARDENAFIL AND PENTOXIFYLLINE EXPERIMENT
Кубанский научный медицинский вестник
эксперимент
хроническая ишемия
нижняя конечность
варденафил
пентоксифиллин
experiment
chronic ischemia of the lower limb
vardenafil
pentoxifylline
author_facet K. I. Lavrinenko
A. S. Belous
G. S. Mal
E. B. Artyushkova
E. A. Loyko
author_sort K. I. Lavrinenko
title CORRECTION CHRONIC ISCHEMIA FINITE COMBINATION OF VARDENAFIL AND PENTOXIFYLLINE EXPERIMENT
title_short CORRECTION CHRONIC ISCHEMIA FINITE COMBINATION OF VARDENAFIL AND PENTOXIFYLLINE EXPERIMENT
title_full CORRECTION CHRONIC ISCHEMIA FINITE COMBINATION OF VARDENAFIL AND PENTOXIFYLLINE EXPERIMENT
title_fullStr CORRECTION CHRONIC ISCHEMIA FINITE COMBINATION OF VARDENAFIL AND PENTOXIFYLLINE EXPERIMENT
title_full_unstemmed CORRECTION CHRONIC ISCHEMIA FINITE COMBINATION OF VARDENAFIL AND PENTOXIFYLLINE EXPERIMENT
title_sort correction chronic ischemia finite combination of vardenafil and pentoxifylline experiment
publisher Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
series Кубанский научный медицинский вестник
issn 1608-6228
2541-9544
publishDate 2016-10-01
description Experimental work conducted on Wistar rat line. Ischemia was simulated on the shin muscles of rats. Muscle ischaemia correction performed intragastric administration of pentoxifylline at a dose of 60 mg / kg of vardenafil dose of 0.9 mg / kg daily for 28 days and in combination vardenafil dose of 0.09 mg / kg of pentoxifylline and 30 mg / kg for 7 days. Results were evaluated 21 and 28 hours. The level of microcirculatory perfusion expressed in units. Correction of muscle ischemia combination of vardenafil and pentoxifylline in small doses for 7 days stimulates angiogenesis and improves blood circulation in the distal extremities in proportion to the average therapeutic dose of vardenafil 28 days.
topic эксперимент
хроническая ишемия
нижняя конечность
варденафил
пентоксифиллин
experiment
chronic ischemia of the lower limb
vardenafil
pentoxifylline
url https://ksma.elpub.ru/jour/article/view/595
work_keys_str_mv AT kilavrinenko correctionchronicischemiafinitecombinationofvardenafilandpentoxifyllineexperiment
AT asbelous correctionchronicischemiafinitecombinationofvardenafilandpentoxifyllineexperiment
AT gsmal correctionchronicischemiafinitecombinationofvardenafilandpentoxifyllineexperiment
AT ebartyushkova correctionchronicischemiafinitecombinationofvardenafilandpentoxifyllineexperiment
AT ealoyko correctionchronicischemiafinitecombinationofvardenafilandpentoxifyllineexperiment
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