Crystal structures of two new 3-(2-chloroethyl)-r(2),c(6)-diarylpiperidin-4-ones

Crystal structures of two new 3-(2-chloroethyl)-r(2),c(6)-diarylpiperidin-4-ones

The syntheses and crystal structures of 3-(2-chloroethyl)-r-2,c-6-diphenylpiperidin-4-one, C19H20ClNO, (I), and 3-(2-chloroethyl)-r-2,c-6-bis(4-fluorophenyl)piperidin-4-one, C19H18ClF2NO, (II), are described. The piperidone ring adopts a chair conformation in (I), whereas a slightly distorted chair...

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Bibliographic Details
Main Authors: K. Rajkumar, S. Sivakumar, R. Arulraj, Manpreet Kaur, Jerry P. Jasinski, A. Manimekalai, A. Thiruvalluvar
Format: Article
Language:English
Published: International Union of Crystallography 2018-04-01
Series:Acta Crystallographica Section E: Crystallographic Communications
Subjects:
crystal structure
bifurcated bond
weak intermolecular hydrogen bonds
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2056989018003766
Description
Summary:The syntheses and crystal structures of 3-(2-chloroethyl)-r-2,c-6-diphenylpiperidin-4-one, C19H20ClNO, (I), and 3-(2-chloroethyl)-r-2,c-6-bis(4-fluorophenyl)piperidin-4-one, C19H18ClF2NO, (II), are described. The piperidone ring adopts a chair conformation in (I), whereas a slightly distorted chair conformation is formed in (II). The dihedral angle between the mean plane of the phenyl rings is 59.1 (1)° in (I) and 76.1 (1)° in (II). The crystal packing features weak intermolecular N—H...O hydrogen bonds in each structure.
ISSN:2056-9890

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