MECHANISMS OF RENAL SCARING FROM REFLUX-NEPHROPATHY

There is presentation of paths of the pathogenesis of renal scaring from vesico-ureteral reflux at this article. Author demonstrated the role of macrophage and tissue monocyte in process of the inflammatory remodeling of interstitial renal tissue. Different cell signals affects interstitial tissue a...

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Main Author: M. M. Batyushin
Format: Article
Language:Russian
Published: State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation 2013-06-01
Series:Vestnik Urologii
Subjects:
Online Access:https://www.urovest.ru/jour/article/view/46
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spelling doaj-12e422eb65374e328a87635c44c846092021-07-28T16:20:47ZrusState Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian FederationVestnik Urologii2308-64242013-06-0102435110.21886/2308-6424-2013-0-2-43-5146MECHANISMS OF RENAL SCARING FROM REFLUX-NEPHROPATHYM. M. Batyushin0Department of Internal Disease with Physiotherapy №2, Problematic Science Laboratory of Experimental Nephrology Rostov State Medical University, Rostov-on-Don South Federal University, Science Institution of BiologyThere is presentation of paths of the pathogenesis of renal scaring from vesico-ureteral reflux at this article. Author demonstrated the role of macrophage and tissue monocyte in process of the inflammatory remodeling of interstitial renal tissue. Different cell signals affects interstitial tissue and activates fibroblast ploliferation and interstitial volume increasing. Cytokines such us monocyte chemotactic peptide-1, epidermal growth factor, macrophage colony stimulating factor, transforming growth factor-β1plays important role within process renal scaring and remodeling. Urinary tract infection causes expressed medullar renal scaring by toxins and inductive endogenic cytokines.https://www.urovest.ru/jour/article/view/46vesico-ureteral refluxreflux-nephropathycytokinesrenal scaringurinary tract infection
collection DOAJ
language Russian
format Article
sources DOAJ
author M. M. Batyushin
spellingShingle M. M. Batyushin
MECHANISMS OF RENAL SCARING FROM REFLUX-NEPHROPATHY
Vestnik Urologii
vesico-ureteral reflux
reflux-nephropathy
cytokines
renal scaring
urinary tract infection
author_facet M. M. Batyushin
author_sort M. M. Batyushin
title MECHANISMS OF RENAL SCARING FROM REFLUX-NEPHROPATHY
title_short MECHANISMS OF RENAL SCARING FROM REFLUX-NEPHROPATHY
title_full MECHANISMS OF RENAL SCARING FROM REFLUX-NEPHROPATHY
title_fullStr MECHANISMS OF RENAL SCARING FROM REFLUX-NEPHROPATHY
title_full_unstemmed MECHANISMS OF RENAL SCARING FROM REFLUX-NEPHROPATHY
title_sort mechanisms of renal scaring from reflux-nephropathy
publisher State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation
series Vestnik Urologii
issn 2308-6424
publishDate 2013-06-01
description There is presentation of paths of the pathogenesis of renal scaring from vesico-ureteral reflux at this article. Author demonstrated the role of macrophage and tissue monocyte in process of the inflammatory remodeling of interstitial renal tissue. Different cell signals affects interstitial tissue and activates fibroblast ploliferation and interstitial volume increasing. Cytokines such us monocyte chemotactic peptide-1, epidermal growth factor, macrophage colony stimulating factor, transforming growth factor-β1plays important role within process renal scaring and remodeling. Urinary tract infection causes expressed medullar renal scaring by toxins and inductive endogenic cytokines.
topic vesico-ureteral reflux
reflux-nephropathy
cytokines
renal scaring
urinary tract infection
url https://www.urovest.ru/jour/article/view/46
work_keys_str_mv AT mmbatyushin mechanismsofrenalscaringfromrefluxnephropathy
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