Mechanisms of Trained Innate Immunity in oxLDL Primed Human Coronary Smooth Muscle Cells

Mechanisms of Trained Innate Immunity in oxLDL Primed Human Coronary Smooth Muscle Cells

Objective: Damage and pathogen associated molecular patterns such as oxidized low-density lipoprotein (oxLDL) or bacillus Calmette-Guerin (BCG) vaccine can induce long term pro-inflammatory priming in monocytes and macrophages due to metabolic and epigenetic reprogramming—an emerging new concept cal...

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Bibliographic Details
Main Authors: Lucia Schnack, Yahya Sohrabi, Sina M. M. Lagache, Florian Kahles, Dennis Bruemmer, Johannes Waltenberger, Hannes M. Findeisen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
trained innate immunity
smooth muscle cells
inflammation
oxLDL
mTOR
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00013/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00013/full

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