Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): study protocol for a pilot randomized controlled trial

Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): study protocol for a pilot randomized controlled trial

Abstract Background Trauma is the leading cause of morbidity and mortality in children in the United States. The antifibrinolytic drug tranexamic acid (TXA) improves survival in adults with traumatic hemorrhage, however, the drug has not been evaluated in a clinical trial in severely injured childre...

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Bibliographic Details
Main Authors: Daniel K. Nishijima, John VanBuren, Hilary A. Hewes, Sage R. Myers, Rachel M. Stanley, P. David Adelson, Sarah E. Barnhard, Matthew Bobinski, Simona Ghetti, James F. Holmes, Ian Roberts, Walton O. Schalick, Nam K. Tran, Leah S. Tzimenatos, J. Michael Dean, Nathan Kuppermann, for the TIC-TOC Collaborators of the Pediatric Emergency Care Applied Research Network
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Trials
Subjects:
Children
Trauma
Tranexamic acid
Online Access:http://link.springer.com/article/10.1186/s13063-018-2974-z

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