Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles

Tumour samples are heterogeneous and are comprised of multiple cell types in addition to cancer cells. Here, the authors devised a method to estimate the relative levels of haematopoietic cells in breast cancer samples and demonstrate that this correlates with prognosis.

Bibliographic Details
Main Authors: Frederick S. Varn, Erik H. Andrews, David W. Mullins, Chao Cheng
Format: Article
Language:English
Published: Nature Publishing Group 2016-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10248
Description
Summary:Tumour samples are heterogeneous and are comprised of multiple cell types in addition to cancer cells. Here, the authors devised a method to estimate the relative levels of haematopoietic cells in breast cancer samples and demonstrate that this correlates with prognosis.
ISSN:2041-1723