Potential bias in ophthalmic pharmaceutical clinical trials
Paul VarnerJohn J Pershing Veterans’ Administration Medical Center, Poplar Bluff, Missouri, USAAbstract: To make clinicians aware of potential sources of error in ophthalmic pharmaceutical clinical trials that can lead to erroneous interpretation of results, a critical review of the st...
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2008-06-01
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doaj-12c8bb65eba64033ac521bbd993f403b2020-11-24T22:58:28ZengDove Medical PressClinical Ophthalmology1177-54671177-54832008-06-012008Issue 2401411Potential bias in ophthalmic pharmaceutical clinical trialsPaul VarnerPaul VarnerJohn J Pershing Veterans’ Administration Medical Center, Poplar Bluff, Missouri, USAAbstract: To make clinicians aware of potential sources of error in ophthalmic pharmaceutical clinical trials that can lead to erroneous interpretation of results, a critical review of the study design of various pharmaceutical ophthalmic clinical trials was completed. Discrepancies as a result of study shortcomings may explain observed differences between reported ophthalmic trial data and observed clinical results.Keywords: evidence-based medicine, validity, bias, gold standard http://www.dovepress.com/potential-bias-in-ophthalmic-pharmaceutical-clinical-trials-a1795 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Paul Varner |
spellingShingle |
Paul Varner Potential bias in ophthalmic pharmaceutical clinical trials Clinical Ophthalmology |
author_facet |
Paul Varner |
author_sort |
Paul Varner |
title |
Potential bias in ophthalmic pharmaceutical clinical trials |
title_short |
Potential bias in ophthalmic pharmaceutical clinical trials |
title_full |
Potential bias in ophthalmic pharmaceutical clinical trials |
title_fullStr |
Potential bias in ophthalmic pharmaceutical clinical trials |
title_full_unstemmed |
Potential bias in ophthalmic pharmaceutical clinical trials |
title_sort |
potential bias in ophthalmic pharmaceutical clinical trials |
publisher |
Dove Medical Press |
series |
Clinical Ophthalmology |
issn |
1177-5467 1177-5483 |
publishDate |
2008-06-01 |
description |
Paul VarnerJohn J Pershing Veterans’ Administration Medical Center, Poplar Bluff, Missouri, USAAbstract: To make clinicians aware of potential sources of error in ophthalmic pharmaceutical clinical trials that can lead to erroneous interpretation of results, a critical review of the study design of various pharmaceutical ophthalmic clinical trials was completed. Discrepancies as a result of study shortcomings may explain observed differences between reported ophthalmic trial data and observed clinical results.Keywords: evidence-based medicine, validity, bias, gold standard |
url |
http://www.dovepress.com/potential-bias-in-ophthalmic-pharmaceutical-clinical-trials-a1795 |
work_keys_str_mv |
AT paulvarner potentialbiasinophthalmicpharmaceuticalclinicaltrials |
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