Potential bias in ophthalmic pharmaceutical clinical trials
Paul VarnerJohn J Pershing Veterans’ Administration Medical Center, Poplar Bluff, Missouri, USAAbstract: To make clinicians aware of potential sources of error in ophthalmic pharmaceutical clinical trials that can lead to erroneous interpretation of results, a critical review of the st...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2008-06-01
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| Series: | Clinical Ophthalmology |
| Online Access: | http://www.dovepress.com/potential-bias-in-ophthalmic-pharmaceutical-clinical-trials-a1795 |
| Summary: | Paul VarnerJohn J Pershing Veterans’ Administration Medical Center, Poplar Bluff, Missouri, USAAbstract: To make clinicians aware of potential sources of error in ophthalmic pharmaceutical clinical trials that can lead to erroneous interpretation of results, a critical review of the study design of various pharmaceutical ophthalmic clinical trials was completed. Discrepancies as a result of study shortcomings may explain observed differences between reported ophthalmic trial data and observed clinical results.Keywords: evidence-based medicine, validity, bias, gold standard |
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| ISSN: | 1177-5467 1177-5483 |