Technical aspects of circulating tumor cells (CTC) isolation using molecular sieve

• Main Authors: Paweł Pastuszka, Zdzisław Bogdanowicz, Artur Kowalik, Krzysztof Gruszczyński, Mariusz Łapiński
• Format: Article
• Language: English
• Published: Wojskowa Akademia Techniczna, Redakcja Wydawnictw WAT, ul. gen. S. Kaliskiego 2, 00-908 Warszawa 2017-03-01
• Series: Biuletyn Wojskowej Akademii Technicznej
• Subjects: molecular sieves; circulating tumor cells (CTC) enrichment; laser photolithography; laser ablation
• Online Access: http://biuletynwat.pl/gicid/01.3001.0009.9483

The article presents the characteristics of circulating tumor cells (CTC) in the context of their enrichment. It presents the possibility of the use of molecular sieves in CTC isolation. It shows important technical factors affecting the efficiency of CTC enrichment using molecular sieves and indicates the necessity of compromise choice of these parameters. It shows 2D molecular sieve construction made within the Biomedical Engineering Centre of MUT. It presents the future directions of research which assumes the use of this construction for a molecular filter in the form of sieve stack. Keywords: molecular sieves, circulating tumor cells (CTC) enrichment, laser photolithography, laser ablation