Collagen/hyaluronan based hydrogels releasing sulfated hyaluronan improve dermal wound healing in diabetic mice via reducing inflammatory macrophage activity

Collagen/hyaluronan based hydrogels releasing sulfated hyaluronan improve dermal wound healing in diabetic mice via reducing inflammatory macrophage activity

Sustained inflammation associated with dysregulated macrophage activation prevents tissue formation and healing of chronic wounds. Control of inflammation and immune cell functions thus represents a promising approach in the development of advanced therapeutic strategies. Here we describe immunomodu...

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Bibliographic Details
Main Authors: Sophia Hauck, Paula Zager, Norbert Halfter, Elke Wandel, Marta Torregrossa, Ainur Kakpenova, Sandra Rother, Michelle Ordieres, Susann Räthel, Albrecht Berg, Stephanie Möller, Matthias Schnabelrauch, Jan C. Simon, Vera Hintze, Sandra Franz
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-12-01
Series:Bioactive Materials
Subjects:
4–6): sulfated hyaluronan
Macrophages
Immunomodulation
Chronic wounds
Hydrogel
Skin inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2100195X

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