Melatonin protects the heart and pancreas by improving glucose homeostasis, oxidative stress, inflammation and apoptosis in T2DM-induced rats

Melatonin protects the heart and pancreas by improving glucose homeostasis, oxidative stress, inflammation and apoptosis in T2DM-induced rats

Cardiomyopathy and pancreatic injury are health issues associated with type 2 diabetes mellitus (T2DM) and are characterized by elevated oxidative stress, inflammation and apoptosis. Melatonin (MLT) is a hormone with multifunctional antioxidant activity. The protective effects of MLT on the heart an...

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Bibliographic Details
Main Authors: Doaa A. Abdulwahab, Mohamed A. El-Missiry, Sameh Shabana, Azza I. Othman, Maggie E. Amer
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Heliyon
Subjects:
Melatonin
Heart
Pancreas
Oxidative stress
Inflammatory cytokines
Hyperglycemia
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402100579X

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