Mild myelin disruption elicits early alteration in behavior and proliferation in the subventricular zone

Mild myelin disruption elicits early alteration in behavior and proliferation in the subventricular zone

Myelin, the insulating sheath around axons, supports axon function. An important question is the impact of mild myelin disruption. In the absence of the myelin protein proteolipid protein (PLP1), myelin is generated but with age, axonal function/maintenance is disrupted. Axon disruption occurs in Pl...

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Bibliographic Details
Main Authors: Elizabeth A Gould, Nicolas Busquet, Douglas Shepherd, Robert M Dietz, Paco S Herson, Fabio M Simoes de Souza, Anan Li, Nicholas M George, Diego Restrepo, Wendy B Macklin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-02-01
Series:eLife
Subjects:
oligodendrocyte
demyelination
olfaction
sub ventricular zone
motor coordination
cognition
Online Access:https://elifesciences.org/articles/34783

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