Visible light-induced direct α C–H functionalization of alcohols
Alcohols are very useful building blocks in organic synthesis, however C–H functionaliztion in presence of free –OH groups is highly challenging. Here, the authors report a selective visible light-promoted α-functionalization of free alcohols with heteroarenes mediated by Selectofluor.
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| Format: | Article |
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Nature Publishing Group
2019-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-08413-9 |
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doaj-12a8b47afd99453b9fd4578a86b1235e2021-05-11T11:37:19ZengNature Publishing GroupNature Communications2041-17232019-01-011011710.1038/s41467-019-08413-9Visible light-induced direct α C–H functionalization of alcoholsLinbin Niu0Jiamei Liu1Xing-An Liang2Shengchun Wang3Aiwen Lei4College of Chemistry and Molecular Sciences, the Institute for Advanced Studies (IAS), Wuhan UniversityCollege of Chemistry and Molecular Sciences, the Institute for Advanced Studies (IAS), Wuhan UniversityCollege of Chemistry and Molecular Sciences, the Institute for Advanced Studies (IAS), Wuhan UniversityCollege of Chemistry and Molecular Sciences, the Institute for Advanced Studies (IAS), Wuhan UniversityCollege of Chemistry and Molecular Sciences, the Institute for Advanced Studies (IAS), Wuhan UniversityAlcohols are very useful building blocks in organic synthesis, however C–H functionaliztion in presence of free –OH groups is highly challenging. Here, the authors report a selective visible light-promoted α-functionalization of free alcohols with heteroarenes mediated by Selectofluor.https://doi.org/10.1038/s41467-019-08413-9 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Linbin Niu Jiamei Liu Xing-An Liang Shengchun Wang Aiwen Lei |
| spellingShingle |
Linbin Niu Jiamei Liu Xing-An Liang Shengchun Wang Aiwen Lei Visible light-induced direct α C–H functionalization of alcohols Nature Communications |
| author_facet |
Linbin Niu Jiamei Liu Xing-An Liang Shengchun Wang Aiwen Lei |
| author_sort |
Linbin Niu |
| title |
Visible light-induced direct α C–H functionalization of alcohols |
| title_short |
Visible light-induced direct α C–H functionalization of alcohols |
| title_full |
Visible light-induced direct α C–H functionalization of alcohols |
| title_fullStr |
Visible light-induced direct α C–H functionalization of alcohols |
| title_full_unstemmed |
Visible light-induced direct α C–H functionalization of alcohols |
| title_sort |
visible light-induced direct α c–h functionalization of alcohols |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2019-01-01 |
| description |
Alcohols are very useful building blocks in organic synthesis, however C–H functionaliztion in presence of free –OH groups is highly challenging. Here, the authors report a selective visible light-promoted α-functionalization of free alcohols with heteroarenes mediated by Selectofluor. |
| url |
https://doi.org/10.1038/s41467-019-08413-9 |
| work_keys_str_mv |
AT linbinniu visiblelightinduceddirectachfunctionalizationofalcohols AT jiameiliu visiblelightinduceddirectachfunctionalizationofalcohols AT xinganliang visiblelightinduceddirectachfunctionalizationofalcohols AT shengchunwang visiblelightinduceddirectachfunctionalizationofalcohols AT aiwenlei visiblelightinduceddirectachfunctionalizationofalcohols |
| _version_ |
1721446147019505664 |