2’-fucosyllactose Supplementation Improves Gut-Brain Signaling and Diet-Induced Obese Phenotype and Changes the Gut Microbiota in High Fat-Fed Mice

2’-fucosyllactose Supplementation Improves Gut-Brain Signaling and Diet-Induced Obese Phenotype and Changes the Gut Microbiota in High Fat-Fed Mice

Obesity is characterized by fat accumulation, chronic inflammation and impaired satiety signaling, which may be due in part to gut microbial dysbiosis. Manipulations of the gut microbiota and its metabolites are attractive targets for obesity treatment. The predominant oligosaccharide found in human...

Full description

Bibliographic Details
Main Authors: Sunhye Lee, Michael Goodson, Wendie Vang, Karen Kalanetra, Daniela Barile, Helen Raybould
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Nutrients
Subjects:
2’-fucosyllactose
gut microbiota and metabolites
gut-brain axis
intestinal epithelial permeability
inflammation
diet-induced obesity
Online Access:https://www.mdpi.com/2072-6643/12/4/1003

Similar Items

Similar Items