Evaluation of Fast Molecular Detection of Lymph Node Metastases in Prostate Cancer Patients Using One-Step Nucleic Acid Amplification (OSNA)

Evaluation of Fast Molecular Detection of Lymph Node Metastases in Prostate Cancer Patients Using One-Step Nucleic Acid Amplification (OSNA)

<i>Background</i>: In clinical routine, only fractions of lymph nodes (LNs) are examined histopathologically, often resulting in missed (micro-)metastases and incorrect staging of prostate cancer (PCa). One-step nucleic acid amplification (OSNA) analyzes the entire LN by detecting cytoke...

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Bibliographic Details
Main Authors: Svenja Engels, Lutz Brautmeier, Lena Reinhardt, Clara Wasylow, Friederike Hasselmann, Rolf P. Henke, Friedhelm Wawroschek, Alexander Winter
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
cytokeratin 19
metastases
OSNA
prostate cancer
sentinel lymph node
Online Access:https://www.mdpi.com/2072-6694/13/5/1117

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