Distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain

Thalamocortical dysrhythmia is a key pathology of chronic pain. Here, the authors propose an analytical pipeline to study dynamic fMRI brain networks and demonstrate that chronic low back pain pathophysiology and clinical pain intensity are associated with distinct thalamocortical network dynamics.

Bibliographic Details
Main Authors: Yiheng Tu, Zening Fu, Cuiping Mao, Maryam Falahpour, Randy L. Gollub, Joel Park, Georgia Wilson, Vitaly Napadow, Jessica Gerber, Suk-Tak Chan, Robert R. Edwards, Ted J. Kaptchuk, Thomas Liu, Vince Calhoun, Bruce Rosen, Jian Kong
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17788-z