ROLE OF IL-6 IN EXPERIMENTAL ARTHRITIS CAUSED BY TRANSFER OF ARTHRITOGENIC ANTIBODIES

ROLE OF IL-6 IN EXPERIMENTAL ARTHRITIS CAUSED BY TRANSFER OF ARTHRITOGENIC ANTIBODIES

Interleukin-6 (IL-6) exerts important functions on immune regulation. In case of high expression, IL-6 may promote autoimmune disorders, e.g., arthritis. Systemic IL-6 blockers based on monoclonal antibodies against IL-6, or its specific receptor subunit, are already used in clinical settings, addin...

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Bibliographic Details
Main Authors: M. S. Drutskaya, E. A. Gorshkova, A. S. Zhdanova, K.-S. Atretkhany, V. S. Gogoleva, R. V. Zvartsev, A. A. Kruglov, S. A. Nedospasov
Format: Article
Language:Russian
Published: SPb RAACI 2016-12-01
Series:Medicinskaâ Immunologiâ
Subjects:
interleukin-6
experimental arthritis
anti-collagen antibodies transfer
neutralizing antibodies
tnf
Online Access:https://www.mimmun.ru/mimmun/article/view/1139

Internet

https://www.mimmun.ru/mimmun/article/view/1139

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