Estrogen improved the regeneration of axons after subcortical axon injury via regulation of PI3K/Akt/CDK5/Tau pathway

Abstract Aim To investigate the effect of estrogen on axon regeneration and neurological recovery after subcortical axon injury, and further explore its underlying molecular mechanisms. Method Subcortical axonal fiber injury model was used in this study. Morris water maze was conducted to detect the...

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Bibliographic Details
Main Authors: Xiaohui Xia, Changlong Zhou, Xiaochuan Sun, Xuenong He, Chang Liu, Guanyu Wang
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Brain and Behavior
Subjects:
Tau
Online Access:https://doi.org/10.1002/brb3.1777