Autotransplants in Advanced Non-Hodgkin Lymphoma: Are They Effective?
Recent data suggest that intensive therapy followed by a bone marrow antotransplant is effective in advanced intermediate and high-grade non-Hodgkin lymphoma (predominantly large-cell lymphoma). Twelve studies of autotransplants were analyzed to determine outcome. Results compared to data from 29 ch...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
1992-09-01
|
| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.1177/096368979200100502 |
| Summary: | Recent data suggest that intensive therapy followed by a bone marrow antotransplant is effective in advanced intermediate and high-grade non-Hodgkin lymphoma (predominantly large-cell lymphoma). Twelve studies of autotransplants were analyzed to determine outcome. Results compared to data from 29 chemotherapy studies. Complete remission was reported in 53% of autotransplant recipients versus 17% of persons receiving chemotherapy. Two-year disease-free survival was 16 and 2%, respectively. It is uncertain whether these differences indicate superiority of autotransplants or reflect selection biases. Also unknown is whether similar results might not be obtained with similarly intensive treatment without an autotransplant. |
|---|---|
| ISSN: | 0963-6897 1555-3892 |