In Vivo Testing of MicroRNA-Mediated Gene Knockdown in Zebrafish

The zebrafish (Danio rerio) has become an attractive model for human disease modeling as there are a large number of orthologous genes that encode similar proteins to those found in humans. The number of tools available to manipulate the zebrafish genome is limited and many currently used techniques...

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Bibliographic Details
Main Authors: Ivone Un San Leong, Chuan-Ching Lan, Jonathan R. Skinner, Andrew N. Shelling, Donald R. Love
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2012/350352