Clinical characteristics and outcomes of patients with primary lung adenocarcinoma harboring ALK rearrangements detected by FISH, IHC, and RT-PCR.

Clinical characteristics and outcomes of patients with primary lung adenocarcinoma harboring ALK rearrangements detected by FISH, IHC, and RT-PCR.

EML4-ALK is a new driver gene of non-small cell lung cancer and a target of crizotinib. The objectives of this study were to determine the frequency of ALK rearrangements in a large cohort of patients with primary lung adenocarcinoma and to analyze the association of ALK rearrangements with clinicop...

Full description

Bibliographic Details
Main Authors: Jinghui Wang, Yiran Cai, Yujie Dong, Jingying Nong, Lijuan Zhou, Guimei Liu, Dan Su, Xi Li, Shafei Wu, Xuejing Chen, Na Qin, Xuan Zeng, Haiqing Zhang, Zongde Zhang, Shucai Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4081522?pdf=render

Internet

http://europepmc.org/articles/PMC4081522?pdf=render

Similar Items