Generation <it>in vivo </it>of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs

<p>Abstract</p> <p>Background</p> <p>Optimal techniques for DC generation for immunotherapy in cancer are yet to be established. Study aims were to evaluate: <it>(i) </it>DC activation/maturation milieu (TNF-α +/- IFN-α) and its effects on CD8+ hTERT-specifi...

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Main Authors: Satthaporn Sukchai, Hardwick Nicola R, Bhalla Joti, Habib Nagy A, Farzaneh Farzin, Eremin Jennifer M, Verma Chandan, Robins Richard A, Mc Kechnie Alastair J, Aloysius Mark M, Sreenivasan Thiagarajan, El-Sheemy Mohammed, Eremin Oleg
Format: Article
Language:English
Published: BMC 2009-03-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/7/1/18