MDR1 is Related to Intestinal Epithelial Injury Induced by Acetylsalicylic Acid

MDR1 is Related to Intestinal Epithelial Injury Induced by Acetylsalicylic Acid

Background/Aims: Although the cytotoxicity of aspirin against the intestinal epithelium is a major clinical problem, little is known about its pathogenesis. We assessed the involvement of Multi Drug Resistance (MDR) 1 in intestinal epithelial cell injury caused by aspirin using MDR1 gene-transfected...

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Main Authors: Munehiro Kugai, Kazuhiko Uchiyama, Toshifumi Tsuji, Hiroyuki Yoriki, Akifumi Fukui, Ying Qin, Yasuki Higashimura, Katsura Mizushima, Naohisa Yoshida, Kazuhiro Katada, Kazuhiro Kamada, Osamu Handa, Tomohisa Takagi, Hideyuki Konishi, Nobuaki Yagi, Toshikazu Yoshikawa, Yoshiyuki Shirasaka, Ikumi Tamai, Yuji Naito, Yoshito Itoh
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
MDR1
Aspirin
Intestinal epithelial injury
Online Access:http://www.karger.com/Article/FullText/354497

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