Knockdown of Pnpla6 protein results in motor neuron defects in zebrafish
SUMMARY Mutations in patatin-like phospholipase domain containing 6 (PNPLA6), also known as neuropathy target esterase (NTE) or SPG39, cause hereditary spastic paraplegia (HSP). Although studies on animal models, including mice and Drosophila, have extended our understanding of PNPLA6, its roles in...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2013-03-01
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Series: | Disease Models & Mechanisms |
Online Access: | http://dmm.biologists.org/content/6/2/404 |