Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient

Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient

We describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosup...

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Main Authors: Akira Tsukada, Taku Fujimura, Sadanori Furudate, Yumi Kambayashi, Akira Hashimoto, Setsuya Aiba
Format: Article
Language:English
Published: Karger Publishers 2012-10-01
Series:Case Reports in Dermatology
Subjects:
Basosquamous cell carcinoma
Immunosuppressive cells
CD163+ M2 macrophage
Carcinogenesis
Online Access:http://www.karger.com/Article/FullText/345095
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spelling doaj-126e0397c5cd44a4a65d584c5a280dea2020-11-24T23:39:39ZengKarger PublishersCase Reports in Dermatology1662-65672012-10-014322723210.1159/000345095345095Basosquamous Cell Carcinoma Developing from a Renal Transplantation RecipientAkira TsukadaTaku FujimuraSadanori FurudateYumi KambayashiAkira HashimotoSetsuya AibaWe describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosuppressive cells, such as regulatory T cells and tumor-associated macrophages. Our present study suggests some of the possible mechanisms for the carcinogenesis of cutaneous malignancy in RTRs.http://www.karger.com/Article/FullText/345095Basosquamous cell carcinomaImmunosuppressive cellsCD163+ M2 macrophageCarcinogenesis
collection DOAJ
language English
format Article
sources DOAJ
author Akira Tsukada
Taku Fujimura
Sadanori Furudate
Yumi Kambayashi
Akira Hashimoto
Setsuya Aiba
spellingShingle Akira Tsukada
Taku Fujimura
Sadanori Furudate
Yumi Kambayashi
Akira Hashimoto
Setsuya Aiba
Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient
Case Reports in Dermatology
Basosquamous cell carcinoma
Immunosuppressive cells
CD163+ M2 macrophage
Carcinogenesis
author_facet Akira Tsukada
Taku Fujimura
Sadanori Furudate
Yumi Kambayashi
Akira Hashimoto
Setsuya Aiba
author_sort Akira Tsukada
title Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient
title_short Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient
title_full Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient
title_fullStr Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient
title_full_unstemmed Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient
title_sort basosquamous cell carcinoma developing from a renal transplantation recipient
publisher Karger Publishers
series Case Reports in Dermatology
issn 1662-6567
publishDate 2012-10-01
description We describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosuppressive cells, such as regulatory T cells and tumor-associated macrophages. Our present study suggests some of the possible mechanisms for the carcinogenesis of cutaneous malignancy in RTRs.
topic Basosquamous cell carcinoma
Immunosuppressive cells
CD163+ M2 macrophage
Carcinogenesis
url http://www.karger.com/Article/FullText/345095
work_keys_str_mv AT akiratsukada basosquamouscellcarcinomadevelopingfromarenaltransplantationrecipient
AT takufujimura basosquamouscellcarcinomadevelopingfromarenaltransplantationrecipient
AT sadanorifurudate basosquamouscellcarcinomadevelopingfromarenaltransplantationrecipient
AT yumikambayashi basosquamouscellcarcinomadevelopingfromarenaltransplantationrecipient
AT akirahashimoto basosquamouscellcarcinomadevelopingfromarenaltransplantationrecipient
AT setsuyaaiba basosquamouscellcarcinomadevelopingfromarenaltransplantationrecipient
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