Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient
We describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosup...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Karger Publishers
2012-10-01
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Series: | Case Reports in Dermatology |
Subjects: | |
Online Access: | http://www.karger.com/Article/FullText/345095 |
Summary: | We describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosuppressive cells, such as regulatory T cells and tumor-associated macrophages. Our present study suggests some of the possible mechanisms for the carcinogenesis of cutaneous malignancy in RTRs. |
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ISSN: | 1662-6567 |