Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient

We describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosup...

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Bibliographic Details
Main Authors: Akira Tsukada, Taku Fujimura, Sadanori Furudate, Yumi Kambayashi, Akira Hashimoto, Setsuya Aiba
Format: Article
Language:English
Published: Karger Publishers 2012-10-01
Series:Case Reports in Dermatology
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Online Access:http://www.karger.com/Article/FullText/345095
Description
Summary:We describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosuppressive cells, such as regulatory T cells and tumor-associated macrophages. Our present study suggests some of the possible mechanisms for the carcinogenesis of cutaneous malignancy in RTRs.
ISSN:1662-6567