Differential Outcomes and Biologic Markers of Radiation-Associated vs. Sporadic Osteosarcoma: A Single-Institution Experience

Differential Outcomes and Biologic Markers of Radiation-Associated vs. Sporadic Osteosarcoma: A Single-Institution Experience

Background: Radiation-associated osteosarcoma (RAO) is a rare, life-threatening complication from radiation. Many physicians presume RAO has a worse prognosis than sporadic osteosarcoma (SO), although limited objective data exist. We conducted a retrospective study comparing these entities.Methods:...

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Bibliographic Details
Main Authors: Brittany L. Siontis, Jonathan B. McHugh, Emily Roberts, Lily Zhao, Dafydd G. Thomas, Dawn Owen, Laurence H. Baker, J. Sybil Biermann, Scott M. Schuetze, Rashmi Chugh
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Oncology
Subjects:
radiation-induced neoplasms
sporadic osteosarcoma
radiation-associated osteosarcoma
secondary malignancy
metastatic tumor antigen-1 (MTA-1)
ezrin
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01523/full

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