Emotional impairment in Parkinson's disease

Emotional impairment is the common complication of Parkinson's disease (PD). Depression, anxiety and apathy affect the quality of life and the prognosis of PD patients. Neuropsychological and neuroimaging studies of emotional impairment in PD patients suggest abnormalities involving mesolimbic...

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Bibliographic Details
Main Authors: Shu-hua LI, Hai-bo CHEN
Format: Article
Language:English
Published: Tianjin Huanhu Hospital 2013-08-01
Series:Chinese Journal of Contemporary Neurology and Neurosurgery
Subjects:
Online Access:http://www.cjcnn.org/index.php/cjcnn/article/view/781
Description
Summary:Emotional impairment is the common complication of Parkinson's disease (PD). Depression, anxiety and apathy affect the quality of life and the prognosis of PD patients. Neuropsychological and neuroimaging studies of emotional impairment in PD patients suggest abnormalities involving mesolimbic and mesocortical dopaminergic pathways, but the specific mechanism needs further study. In this review we discuss the clinical manifestation, possible pathological mechanism, diagnosis and treatment in PD patients. <br />
ISSN:1672-6731